In mechanics, Newton enunciated the principles of conservation of momentum and angular momentum. In optics, he invented the reflecting telescope and developed a theory of colour based on the observation that a prism decomposes white light into a visible spectrum. He also formulated an empirical law of cooling and studied the speed of sound.

In mathematics, Newton shares the credit with Gottfried Leibniz for the development of the differential and integral calculus. He also demonstrated the generalised binomial theorem, developed the so-called "Newton's method" for approximating the zeroes of a function, and contributed to the study of power series.

Newton was also highly religious (though unorthodox), producing more work on Biblical hermeneutics than the natural science he is remembered for today.